
The warden was taken hostage by Michael in an adjacent room. Under duress, Pope made a phone call ordering the guards to transfer Lincoln to the infirmary. The remaining escapees were instructed to assemble in Michael's cell at 7 PM. The inmate who had previously informed to Bellick, now swore his loyalty to Michael and joined the escape attempt.

Outside the prison, Sara finally made her decision and left the infirmary door unlocked to facilitate the escape. Michael and all the others navigated the pipes and converged in the infirmary, where they unexpectedly encountered the mentally ill Haywire, who had also found his way into the system through memory.

Bellick's colleagues discovered his car in the parking lot and initiated a search, eventually finding him in the underground tunnels. Once freed, Bellick organized a search party to hunt down the escapees.
All participants in the escape managed to get over the perimeter wall, except for Westmoreland, who was forced to stay behind due to his severe injuries, and Manche, who fell behind because his weight caused the rope used for scaling the wall to break.