Escobar, who had begun to resist, bombed the chain of pharmacies operated by the Cali Cartel. His act plunged Bogotá into panic, but the "Los Pepes" (People Persecuted by Pablo Escobar) remained unmoved and retaliated even more fiercely. The conflict between the two sides terrified the ordinary people. Los Pepes' next target was Fernando, but he narrowly escaped death.
Given the Castano brothers' indiscriminate killings of innocent people, Peña decided not to cooperate with them and refused to provide any more information. Berna supported Peña's principle of not killing innocent people, but he was unable to stop the Castano brothers' actions.
Panicked, Fernando planned to leave Colombia with his ex-wife and son, but his ex-wife refused. In desperation, Fernando went to pick up his son from school, and the two went into hiding. Meanwhile, Peña ordered the Intelligence Support Activity to track Fernando's location.
To ensure the safety of his family, Escobar booked multiple flights as a decoy. After an emotional farewell with his family, Escobar fainted from excessive stress. The Americans, who learned that Escobar intended to send his family abroad, pressured the Colombian president to use his connections to stop them. The president argued that it was their legal right, but the U.S. ambassador explained the stakes involved, and the Colombian president was persuaded to accept the ambassador's advice.
Mosquera sent Murphy to track Escobar's family, and Murphy kept this matter secret from Peña. The Americans, who found out that Escobar's family was about to flee to Germany, failed in their negotiations with the German side. Helpless, Murphy had to use other methods to ban Escobar's family from entering Germany.
At the same time, Fernando's location was detected. Because Fernando's son was also present, Peña refused to provide Fernando's location to Berna and reported the matter to Mosquera. Peña planned to use safety as a bargaining chip to persuade Fernando to cooperate with them—and succeeded.
However, Trujillo, a police officer who hated Escobar, informed Los Pepes of Fernando's hiding place. Fernando and his son still could not escape being killed. Peña was then summoned by his superior Carr, the mastermind behind Los Pepes, in Berna's name for a talk, and Peña was powerless to do anything about it.
Murphy successfully prevented Escobar's family from entering Germany. Learning this news, Escobar flew into a rage and threatened Germany over the phone. Desperate, Escobar finally turned to Attorney General Grieve for help. The Attorney General placed Escobar's family under protective custody. In retaliation, Escobar ordered his men to plant a bomb near the Presidential Palace, once again harming innocent civilians.