Escobar's empire was on the verge of collapse. Having lost all hope of reversing his fortunes, he returned to his father's rural home and vanished without a trace. The manhunt team could not obtain any information about his whereabouts.
Meanwhile, the issues surrounding the "People Persecuted by Pablo Escobar" (Los Pepes) were being resolved, and the drug lord circle was undergoing a major reshuffle. The Cali Cartel, which had reaped the benefits of others' conflicts, sowed discord between the Castaño brothers and Judy. Determined to eliminate Judy and become the top drug lord in Medellín, the Castaño brothers launched a bomb attack on her while she was out. Fortunately, Judy narrowly escaped death.
Berna summoned Peña. Judy threatened Peña, accusing him of leaking confidential information as a federal agent, and forced him to help her get rid of the Castaño brothers. In response, Peña proposed that Judy cooperate with him as an informant for the anti-narcotics unit to assist in capturing the Cali Cartel.
On the other hand, Tata was extremely anxious as she had been unable to contact Escobar for a long time. Unfortunately, her repeated attempts to reach Escobar via a walkie-talkie were noticed by a guard—who happened to be a friend of Trujillo. The guard reported the matter to Murphy through Trujillo, and Murphy then discussed plans to capture Escobar with Colonel Martínez.
Back at his father's home, Escobar helped with farm work and spent his days in the company of cattle and sheep. During this period, Peña discussed Judy's case with Mosquera, who agreed to his proposal but reminded him that some people disapproved of this arrangement. Carr, one of those who opposed it, had long been aware of everything that was happening.
Berna could not tolerate an informer. He thus reached an agreement with the Cali Cartel and arranged for Judy to be sent out of Colombia. Later, Carr informed Peña that Mosquera had been transferred and that Peña himself would have to prepare to return to his home country. Powerless to change the situation, Peña could only accept the news.
While working alongside his father, Escobar suggested moving to a place near his father with his children, planning to raise a herd of cattle and sheep and start a ranch. However, his father ignored the suggestion. The two finally had an open and honest talk, during which Escobar's father, though it pained him deeply, told Escobar that he was ashamed to have him as a son. Heartbroken, Escobar decided to leave his father's home.
Escobar asked Limón to retrieve the money he had hidden under a tree to fund their departure. Tragically, the money had all rotted away. Desperate for cash, Limón went to Marisa's place. After rummaging through everything, he only found a small amount of money. A quarrel broke out between them, and consumed by resentment over Marisa's previous deception, Limón lost his temper and shot her dead.
Attorney General Grieve advised Tata that if she managed to contact Escobar, she should persuade him to surrender, emphasizing that the law was their last hope. Before leaving, Escobar left the money Limón had obtained for his father and also left behind a photo of himself with his father. He then departed the countryside with Limón. Eventually, Escobar found a location with cell phone signal and successfully got in touch with Tata.